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The following typical symptoms of overdosage have been observed, disturbances of consciousness extending to coma; generalized epileptic fit, hypertension, tachycardia, constricted or dilated pupils, respiratory depression.
These effects can be abolished by administration of an opiate antagonist (e.g. naloxone).
In addition, intensive care measures particularly intubation and ventilation should also be introduced. If fits occur, the use of benzodiazepines should be considered.
